SCOPe 2.04: Domain d1xtfa_: 1xtf A:

Lineage for d1xtfa_ (1xtf A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein Botulinum neurotoxin [55513] (4 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (25 PDB entries)
   Uniprot P10845 1-419

8. Domain d1xtfa_: 1xtf A: [116018]
   complexed with zn; mutant

Details for d1xtfa_

PDB Entry: 1xtf, 2.2 Å

PDB Description: neurotoxin bont/a e224q y366f mutant

PDB Compounds: (A:) Neurotoxin BoNT/A

SCOPe Domain Sequences for d1xtfa_:

Sequence; same for both SEQRES and ATOM records:

>d1xtfa_ d.92.1.7 (A:) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
pfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdlnp
ppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggs
tidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngyg
stqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahqlihaghrlygiainpnr
vfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkak
sivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvl
nrktflnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklknftp
ghhhhhh

Timeline for d1xtfa_:

• d1xtfa_ first appeared in SCOP 1.71
  
• d1xtfa_ appears in SCOPe 2.03
  
• d1xtfa_ appears in SCOPe 2.05
  
• d1xtfa_ appears in the current release, SCOPe 2.08, called d1xtfa1