SCOP 1.75: Domain d1xpmd2: 1xpm D:168-388

Lineage for d1xpmd2 (1xpm D:168-388)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (2 families)

5. Family c.95.1.2: Chalcone synthase-like [53914] (8 proteins)

6. Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS [110760] (1 species)
   most similar to FabH

7. Species Staphylococcus aureus [TaxId:1280] [110761] (5 PDB entries)
   Uniprot Q7A3F6

8. Domain d1xpmd2: 1xpm D:168-388 [115766]
   complexed with caa, hmg, so4

Details for d1xpmd2

PDB Entry: 1xpm, 1.6 Å

PDB Description: crystal structure of staphylococcus aureus hmg-coa synthase with hmg- coa and acetoacetyl-coa and acetylated cysteine

PDB Compounds: (D:) 3-hydroxy-3-methylglutaryl CoA synthase

SCOP Domain Sequences for d1xpmd2:

Sequence; same for both SEQRES and ATOM records:

>d1xpmd2 c.95.1.2 (D:168-388) 3-hydroxy-3-methylglutaryl CoA synthase MvaS {Staphylococcus aureus [TaxId: 1280]}
ilalnedavaytedvydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladf
aslcfhvpftkmgkkalesiidnadettqerlrsgyedavdynryvgniytgslylslis
llenrdlqagetiglfsygsgsvgefysatlvegykdhldqaahkallnnrtevsvdaye
tffkrfddvefdeeqdavhedrhifylsniennvreyhrpe

Timeline for d1xpmd2:

• d1xpmd2 first appeared in SCOP 1.71
  
• d1xpmd2 appears in SCOP 1.73
  
• d1xpmd2 appears in SCOPe 2.01
  
• d1xpmd2 appears in the current release, SCOPe 2.08