SCOPe 2.05: Domain d1xd4a2: 1xd4 A:568-1044

Lineage for d1xd4a2 (1xd4 A:568-1044)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (2 proteins)

6. Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48369] (11 PDB entries)
   Uniprot Q07889 189-1046

8. Domain d1xd4a2: 1xd4 A:568-1044 [115150]
   Other proteins in same PDB: d1xd4a1, d1xd4a3, d1xd4b1, d1xd4b3

Details for d1xd4a2

PDB Entry: 1xd4, 3.64 Å

PDB Description: crystal structure of the dh-ph-cat module of son of sevenless (sos)

PDB Compounds: (A:) Son of sevenless protein homolog 1

SCOPe Domain Sequences for d1xd4a2:

Sequence, based on SEQRES records:

>d1xd4a2 a.117.1.1 (A:568-1044) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
rlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvrtf
lttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvql
rvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiardng
pghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgs
vwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnn
fngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcv
pffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdi
krffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsn

Sequence, based on observed residues (ATOM records):

>d1xd4a2 a.117.1.1 (A:568-1044) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
rlpsadvyrfaepdseeniifeegipiikagtviklierltyhmyadpnfvrtflttyrs
fckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlrvlnvc
rhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiahnitfqsspp
tvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkeinsp
nllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlevvsamn
sspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltnilk
teegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmgn
smekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsn

Timeline for d1xd4a2:

• d1xd4a2 first appeared in SCOP 1.71
  
• d1xd4a2 appears in SCOPe 2.04
  
• d1xd4a2 appears in SCOPe 2.06
  
• d1xd4a2 appears in the current release, SCOPe 2.08