SCOP 1.71: Domain d1xd2c_: 1xd2 C:

Lineage for d1xd2c_ (1xd2 C:)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (1 protein)

6. Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48369] (8 PDB entries)

8. Domain d1xd2c_: 1xd2 C: [115144]
   Other proteins in same PDB: d1xd2a_, d1xd2b_
   complexed with gdp, mg, po4; mutant

Details for d1xd2c_

PDB Entry: 1xd2, 2.7 Å

PDB Description: crystal structure of a ternary ras:sos:ras*gdp complex

SCOP Domain Sequences for d1xd2c_:

Sequence, based on SEQRES records:

>d1xd2c_ a.117.1.1 (C:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens)}
qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
tflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpv
qlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiard
ngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselv
gsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqel
nnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinpp
cvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrves
dikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnp
r

Sequence, based on observed residues (ATOM records):

>d1xd2c_ a.117.1.1 (C:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens)}
qmrlpsadvyrfaepdseeniifeegipiikagtviklierltyhmyadpnfvrtfltty
rsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlrvln
vcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiahnitfqss
pptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkein
spnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlevvsa
mnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltni
lkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpm
gnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnpr

Timeline for d1xd2c_:

• d1xd2c_ is new in SCOP 1.71
  
• d1xd2c_ appears in SCOP 1.73
  
• d1xd2c_ appears in the current release, SCOPe 2.08