SCOP 1.71: Domain d1w76b_: 1w76 B:

Lineage for d1w76b_ (1w76 B:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (35 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (5 proteins)

6. Protein Acetylcholinesterase [53476] (5 species)

7. Species Electric ray (Torpedo californica) [53477] (41 PDB entries)

8. Domain d1w76b_: 1w76 B: [114316]
   complexed with gnt, nag

Details for d1w76b_

PDB Entry: 1w76, 2.3 Å

PDB Description: orthorhombic form of torpedo californica acetylcholinesterase (ache) complexed with bis-acting galanthamine derivative

SCOP Domain Sequences for d1w76b_:

Sequence, based on SEQRES records:

>d1w76b_ c.69.1.1 (B:) Acetylcholinesterase {Electric ray (Torpedo californica)}
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeffpt
slesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvpha
ndlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyff
nhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpn
ephsqeskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

Sequence, based on observed residues (ATOM records):

>d1w76b_ c.69.1.1 (B:) Acetylcholinesterase {Electric ray (Torpedo californica)}
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfsfvpvidgeffptslesml
nsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvphandlgld
avtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyffnhrasn
lvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpnepskwp
lfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

Timeline for d1w76b_:

• d1w76b_ is new in SCOP 1.71
  
• d1w76b_ appears in SCOP 1.73
  
• d1w76b_ appears in the current release, SCOPe 2.08