Lineage for d1ty6h1 (1ty6 H:1-119)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 651989Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)
  6. 652160Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 652522Species Mouse (Mus musculus), cluster 3.1 [TaxId:10090] [88551] (34 PDB entries)
  8. 652553Domain d1ty6h1: 1ty6 H:1-119 [112814]
    Other proteins in same PDB: d1ty6a_, d1ty6b1, d1ty6b2, d1ty6b3, d1ty6h2, d1ty6l1, d1ty6l2
    complexed with ca, gol, hrg, man, mg, mpt, nag, nh2

Details for d1ty6h1

PDB Entry: 1ty6 (more details), 2.9 Å

PDB Description: Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen
PDB Compounds: (H:) monoclonal antibody 10e5 heavy chain

SCOP Domain Sequences for d1ty6h1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ty6h1 b.1.1.1 (H:1-119) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.1 [TaxId: 10090]}

SCOP Domain Coordinates for d1ty6h1:

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Timeline for d1ty6h1: