Lineage for d1txvb2 (1txv B:107-354)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 704292Fold c.62: vWA-like [53299] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
  4. 704293Superfamily c.62.1: vWA-like [53300] (5 families) (S)
  5. 704294Family c.62.1.1: Integrin A (or I) domain [53301] (10 proteins)
  6. 704344Protein Integrin beta A domain [69542] (1 species)
  7. 704345Species Human (Homo sapiens) [TaxId:9606] [69543] (10 PDB entries)
  8. 704346Domain d1txvb2: 1txv B:107-354 [112785]
    Other proteins in same PDB: d1txva_, d1txvb1, d1txvb3, d1txvh1, d1txvh2, d1txvl1, d1txvl2
    complexed with ca, cac, gol, man, mg, nag

Details for d1txvb2

PDB Entry: 1txv (more details), 2.75 Å

PDB Description: Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen
PDB Compounds: (B:) integrin beta-3

SCOP Domain Sequences for d1txvb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1txvb2 c.62.1.1 (B:107-354) Integrin beta A domain {Human (Homo sapiens) [TaxId: 9606]}
vedypvdiyylmdlsysmkddlwsiqnlgtklatqmrkltsnlrigfgafvdkpvspymy
isppealenpcydmkttclpmfgykhvltltdqvtrfneevkkqsvsrnrdapeggfdai
mqatvcdekigwrndashllvfttdakthialdgrlagivqpndgqchvgsdnhysastt
mdypslglmteklsqkninlifavtenvvnlyqnyselipgttvgvlsmdssnvlqlivd
aygkirsk

SCOP Domain Coordinates for d1txvb2:

Click to download the PDB-style file with coordinates for d1txvb2.
(The format of our PDB-style files is described here.)

Timeline for d1txvb2: