SCOPe 2.07: Domain d1t4ka2: 1t4k A:108-212

Lineage for d1t4ka2 (1t4k A:108-212)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (368 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d1t4ka2: 1t4k A:108-212 [112236]
   Other proteins in same PDB: d1t4ka1, d1t4kb1, d1t4kb2, d1t4kc1, d1t4kd1, d1t4kd2
   MQ P01632 P01837 # natural chimera; catalytic antibody with aldolase activity
   complexed with zn

Details for d1t4ka2

PDB Entry: 1t4k, 2.5 Å

PDB Description: Crystal Structure of Unliganded Aldolase Antibody 93F3 Fab

PDB Compounds: (A:) immunoglobulin igg1, kappa light chain

SCOPe Domain Sequences for d1t4ka2:

Sequence; same for both SEQRES and ATOM records:

>d1t4ka2 b.1.1.2 (A:108-212) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
rsdaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrn

Timeline for d1t4ka2:

• d1t4ka2 first appeared in SCOP 1.71
  
• d1t4ka2 appears in SCOPe 2.06
  
• d1t4ka2 appears in the current release, SCOPe 2.08