SCOP 1.75: Domain d1q8ka3: 1q8k A:89-185

Lineage for d1q8ka3 (1q8k A:89-185)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.60: SAM domain-like [47768] (16 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.14: eIF2alpha middle domain-like [116742] (1 family)

5. Family a.60.14.1: eIF2alpha middle domain-like [116743] (1 protein)

6. Protein Eukaryotic initiation factor 2alpha, eIF2alpha, domain 2 [116744] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [116745] (2 PDB entries)
   Uniprot P05198

8. Domain d1q8ka3: 1q8k A:89-185 [111596]
   Other proteins in same PDB: d1q8ka2, d1q8ka4

Details for d1q8ka3

PDB Entry: 1q8k

PDB Description: solution structure of alpha subunit of human eif2

PDB Compounds: (A:) Eukaryotic translation initiation factor 2 subunit 1

SCOP Domain Sequences for d1q8ka3:

Sequence; same for both SEQRES and ATOM records:

>d1q8ka3 a.60.14.1 (A:89-185) Eukaryotic initiation factor 2alpha, eIF2alpha, domain 2 {Human (Homo sapiens) [TaxId: 9606]}
vspeeaikcedkftksktvysilrhvaevleytkdeqleslfqrtawvfddkykrpgyga
ydafkhavsdpsildsldlnederevlinninrrltp

Timeline for d1q8ka3:

• d1q8ka3 first appeared in SCOP 1.71
  
• d1q8ka3 appears in SCOP 1.73
  
• d1q8ka3 appears in SCOPe 2.01
  
• d1q8ka3 appears in the current release, SCOPe 2.08