Class d: Alpha and beta proteins (a+b) [53931] (380 folds) |
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) shares functional and structural similarities with the ATP-grasp fold and PIPK |
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins) members organized in the groups and subfamiles specified by the comments |
Protein Tyrosine-protein kinase Itk/Tsk [111194] (1 species) PTK group; Tec/Atk subfamily; non-membrane spanning protein tyrosine kinase |
Species Human (Homo sapiens) [TaxId:9606] [111195] (28 PDB entries) Uniprot Q08881 357-619 |
Domain d1sm2a_: 1sm2 A: [105754] complexed with stu |
Domain d1sm2b_: 1sm2 B: [105755] complexed with stu |
Domain d1snua_: 1snu A: [105829] complexed with stu |
Domain d1snub_: 1snu B: [105830] complexed with stu |
Domain d1snxa_: 1snx A: [105831] |
Domain d1snxb_: 1snx B: [105832] |
Domain d3miya_: 3miy A: [181293] automated match to d1sm2a_ complexed with b49 |
Domain d3miyb_: 3miy B: [181294] automated match to d1sm2a_ complexed with b49 |
Domain d3mj1a_: 3mj1 A: [181296] automated match to d1sm2a_ complexed with 614 |
Domain d3mj2a_: 3mj2 A: [181297] automated match to d1sm2a_ complexed with mjg |
Domain d3qgwa_: 3qgw A: [233325] automated match to d4kioc_ complexed with l7a, pqc |
Domain d3qgwb_: 3qgw B: [233324] automated match to d4kioc_ complexed with l7a, pqc |
Domain d3qgya_: 3qgy A: [233326] automated match to d4kioc_ complexed with l7o, pqc |
Domain d3qgyb_: 3qgy B: [233327] automated match to d4kioc_ complexed with l7o, pqc |
Domain d3t9ta_: 3t9t A: [185708] automated match to d1sm2a_ complexed with gol, iaq; mutant |
Domain d3v5ja_: 3v5j A: [195400] automated match to d1sm2a_ complexed with 0f2, so4 |
Domain d3v5jb_: 3v5j B: [201197] automated match to d3v8wb_ complexed with 0f2, so4 |
Domain d3v5la_: 3v5l A: [201198] automated match to d3v8wb_ complexed with 0g1, so4 |
Domain d3v5lb_: 3v5l B: [195401] automated match to d1sm2a_ complexed with 0g1, so4 |
Domain d3v5lc_: 3v5l C: [201199] automated match to d3v8wb_ complexed with 0g1, so4 |
Domain d3v5ld_: 3v5l D: [201200] automated match to d3v8wb_ complexed with 0g1, so4 |
Domain d3v8ta_: 3v8t A: [217703] automated match to d3v8wb_ complexed with 477, so4 |
Domain d3v8tb_: 3v8t B: [217704] automated match to d3v8wb_ complexed with 477, so4 |
Domain d3v8wa_: 3v8w A: [201211] automated match to d3v8wb_ complexed with 0g2, so4 |
Domain d3v8wb_: 3v8w B: [195399] automated match to d1sm2a_ complexed with 0g2, so4 |
Domain d4hcta_: 4hct A: [234642] automated match to d4hcua_ complexed with 18r |
Domain d4hcua_: 4hcu A: [193768] automated match to d1sm2a_ complexed with 13l |
Domain d4hcva_: 4hcv A: [234641] automated match to d4hcua_ complexed with 13j |
Domain d4kioa_: 4kio A: [224296] automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
Domain d4kiob_: 4kio B: [224297] automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
Domain d4kioc_: 4kio C: [224298] automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
Domain d4kiod_: 4kio D: [224299] automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
Domain d4l7sa_: 4l7s A: [236195] automated match to d4kioc_ complexed with g7k, so4; mutant |
Domain d4l7sb_: 4l7s B: [236196] automated match to d4kioc_ complexed with g7k, so4; mutant |
Domain d4m0ya_: 4m0y A: [238191] automated match to d4hcua_ complexed with m0y |
Domain d4m0za_: 4m0z A: [238190] automated match to d4hcta_ complexed with m0z |
Domain d4m12a_: 4m12 A: [238189] automated match to d4hcta_ complexed with 1yz |
Domain d4m13a_: 4m13 A: [238188] automated match to d4hcta_ complexed with 1e0 |
Domain d4m14a_: 4m14 A: [238187] automated match to d4hcta_ complexed with qws |
Domain d4m15a_: 4m15 A: [238192] automated match to d4hcta_ complexed with adp, qws |
Domain d4mf0a_: 4mf0 A: [228993] automated match to d4kioa_ complexed with 29z |
Domain d4mf0b_: 4mf0 B: [228994] automated match to d4kioa_ complexed with 29z |
Domain d4mf1a_: 4mf1 A: [228995] automated match to d3miya_ complexed with 29y |
Domain d4mf1b_: 4mf1 B: [228996] automated match to d3miya_ complexed with 29y |
Domain d4pp9b_: 4pp9 B: [257521] automated match to d4kioc_ complexed with 2vt, so4 |
Domain d4pqna_: 4pqn A: [258232] automated match to d3v5jb_ complexed with 2w6, p4g |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase Itk/Tsk: