SCOPe 2.05: Protein: Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase

Lineage for Protein: Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase

Root: SCOPe 2.05
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)
Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (17 proteins)
N-terminal all-beta domain defines family
Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase [110405] (1 species)

Species:

Guinea pig (Cavia porcellus) [TaxId:10141] [110406] (4 PDB entries)
Uniprot Q9EQZ5
1. Domains for 1v3t:
  1. Domain d1v3ta2: 1v3t A:113-294 [108338]
    Other proteins in same PDB: d1v3ta1, d1v3tb1
    complexed with nap
  2. Domain d1v3tb2: 1v3t B:113-294 [108340]
    Other proteins in same PDB: d1v3ta1, d1v3tb1
    complexed with nap
2. Domains for 1v3u:
  1. Domain d1v3ua2: 1v3u A:113-294 [108342]
    Other proteins in same PDB: d1v3ua1, d1v3ub1
    complexed with cl
  2. Domain d1v3ub2: 1v3u B:113-294 [108344]
    Other proteins in same PDB: d1v3ua1, d1v3ub1
    complexed with cl
3. Domains for 1v3v:
  1. Domain d1v3va2: 1v3v A:113-294 [108346]
    Other proteins in same PDB: d1v3va1, d1v3vb1
    complexed with 5op, cl, nap
  2. Domain d1v3vb2: 1v3v B:113-294 [108348]
    Other proteins in same PDB: d1v3va1, d1v3vb1
    complexed with 5op, cl, nap
4. Domains for 2dm6:
  1. Domain d2dm6a2: 2dm6 A:113-294 [131568]
    Other proteins in same PDB: d2dm6a1, d2dm6b1
    automated match to d1v3va2
    complexed with imn, nap, tam
  2. Domain d2dm6b2: 2dm6 B:113-294 [131570]
    Other proteins in same PDB: d2dm6a1, d2dm6b1
    automated match to d1v3va2
    complexed with imn, nap, tam

More info for Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain

Timeline for Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain:

Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain first appeared in SCOP 1.69
Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain appears in SCOPe 2.04
Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain appears in SCOPe 2.06
Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain appears in the current release, SCOPe 2.08