SCOPe 2.02: Domain d1wd8a3: 1wd8 A:294-663

Lineage for d1wd8a3 (1wd8 A:294-663)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.126: Pentein, beta/alpha-propeller [55908] (1 superfamily)
   duplication: composed of 5 alpha-beta(2)-alpha-beta units arranged around pseudo fivefold axis

4. Superfamily d.126.1: Pentein [55909] (8 families)

5. Family d.126.1.5: Peptidylarginine deiminase Pad4, catalytic C-terminal domain [111152] (1 protein)
   # functionally related to the amidinotransferase, similar active sites

6. Protein Peptidylarginine deiminase Pad4, catalytic C-terminal domain [111153] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [111154] (7 PDB entries)
   Uniprot Q9UM07

8. Domain d1wd8a3: 1wd8 A:294-663 [109239]
   Other proteins in same PDB: d1wd8a1, d1wd8a2

Details for d1wd8a3

PDB Entry: 1wd8, 2.8 Å

PDB Description: Calcium free form of human peptidylarginine deiminase type4 (PAD4)

PDB Compounds: (A:) Protein-arginine deiminase type IV

SCOPe Domain Sequences for d1wd8a3:

Sequence, based on SEQRES records:

>d1wd8a3 d.126.1.5 (A:294-663) Peptidylarginine deiminase Pad4, catalytic C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
apwimtpntqppqevyacsifenedflksvttlamkakcklticpeeenmddqwmqdeme
igyiqaphktlpvvfdsprnrglkefpikrvmgpdfgyvtrgpqtggisgldsfgnlevs
ppvtvrgkeyplgrilfgdscypsndsrqmhqalqdflsaqqvqapvklysdwlsvghvd
eflsfvpapdrkgfrlllasprscyklfqeqqneghgeallfegikkkkqqkiknilsnk
tlrehnsfvercidwnrellkrelglaesdiidipqlfklkefskaeaffpnmvnmlvlg
khlgipkpfgpvingrccleekvcslleplglqctfindfftyhirhgevhcgtnvrrkp
fsfkwwnmvp

Sequence, based on observed residues (ATOM records):

>d1wd8a3 d.126.1.5 (A:294-663) Peptidylarginine deiminase Pad4, catalytic C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
apwimtpntqppqevyacslksvttlamkakcklticqdemeigyiqaphktlpvvfdsd
fgyvtrggldsfgnlevsppvtvrgkeyplgrilfgdscypsndsrqmhqalqdflsaqq
vqapvklysdwlsvghvdeflsfvpapdrkgfrlllasprscyklfqeqqneghgeallf
kqqkiknilsnktlrehnsfvercidwnrellkrelglaesdiidipqlfklkefskaea
ffpnmvnmlvlgkhlgipkpfgpvingrccleekvcslleplglqctfindcgtnvrrkp
fsfkwwnmvp

Timeline for d1wd8a3:

• d1wd8a3 first appeared in SCOP 1.69
  
• d1wd8a3 appears in SCOPe 2.01
  
• d1wd8a3 appears in SCOPe 2.03
  
• d1wd8a3 appears in the current release, SCOPe 2.08