SCOPe 2.06: Domain d1u67a1: 1u67 A:74-584

Lineage for d1u67a1 (1u67 A:74-584)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (4 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (3 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Sheep (Ovis aries) [TaxId:9940] [48137] (23 PDB entries)
   Uniprot P05979 32-584

8. Domain d1u67a1: 1u67 A:74-584 [107697]
   Other proteins in same PDB: d1u67a2
   complexed with acd, bog, coh; mutant

Details for d1u67a1

PDB Entry: 1u67, 3.1 Å

PDB Description: crystal structure of arachidonic acid bound to a mutant of prostagladin h synthase-1 that forms predominantly 11-hpete.

PDB Compounds: (A:) Prostaglandin G/H synthase 1 precursor

SCOPe Domain Sequences for d1u67a1:

Sequence; same for both SEQRES and ATOM records:

>d1u67a1 a.93.1.2 (A:74-584) Prostaglandin H2 synthase {Sheep (Ovis aries) [TaxId: 9940]}
iwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptynia
hdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqg
tnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklk
yqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvc
dllkaehptwgdeqlfqtarliligetikivieeyaqqlsgyflqlkfdpellfgaqfqy
rnriamefnqlyhfhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagr
igggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaelee
lygdidalefypglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfgge
vgfnlvktatlkklvclntktcpyvsfhvpd

Timeline for d1u67a1:

• d1u67a1 first appeared in SCOP 1.69
  
• d1u67a1 appears in SCOPe 2.05
  
• d1u67a1 appears in SCOPe 2.07
  
• d1u67a1 appears in the current release, SCOPe 2.08