SCOP 1.73: Domain d1u4da_: 1u4d A:

Lineage for d1u4da_ (1u4d A:)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Activated CDC42 kinase 1, ACK1 [111200] (1 species)
   PTK group; Tck subfamily; non-membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [111201] (3 PDB entries)

8. Domain d1u4da_: 1u4d A: [107668]

Details for d1u4da_

PDB Entry: 1u4d, 2.1 Å

PDB Description: Structure of the ACK1 Kinase Domain bound to Debromohymenialdisine

PDB Compounds: (A:) Activated CDC42 kinase 1

SCOP Domain Sequences for d1u4da_:

Sequence, based on SEQRES records:

>d1u4da_ d.144.1.7 (A:) Activated CDC42 kinase 1, ACK1 {Human (Homo sapiens) [TaxId: 9606]}
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfaw
capeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedc
pqdiynvmvqcwahkpedrptfvalrdflleaq

Sequence, based on observed residues (ATOM records):

>d1u4da_ d.144.1.7 (A:) Activated CDC42 kinase 1, ACK1 {Human (Homo sapiens) [TaxId: 9606]}
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkcpeamddfirevnamhsl
dhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqvaegmgyle
skrfihrdlaarnlllatrdlvkigdfglmralpqdhyvmvpfawcapeslktrtfshas
dtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqdiynvmvqcwahk
pedrptfvalrdflleaq

Timeline for d1u4da_:

• d1u4da_ first appeared in SCOP 1.69
  
• d1u4da_ appears in SCOP 1.71
  
• d1u4da_ appears in SCOP 1.75
  
• d1u4da_ appears in the current release, SCOPe 2.08