SCOPe 2.05: Domain d1tzhw_: 1tzh W:

Lineage for d1tzhw_ (1tzh W:)

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.1: Platelet-derived growth factor-like [57502] (4 proteins)

6. Protein Vascular endothelial growth factor, VEGF [57505] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57506] (17 PDB entries)
   Uniprot P15692 40-133

8. Domain d1tzhw_: 1tzh W: [107486]
   Other proteins in same PDB: d1tzha1, d1tzha2, d1tzhb1, d1tzhb2, d1tzhh1, d1tzhh2, d1tzhl1, d1tzhl2

Details for d1tzhw_

PDB Entry: 1tzh, 2.6 Å

PDB Description: Crystal Structure of the Fab YADS1 Complexed with h-VEGF

PDB Compounds: (W:) Vascular Endothelial Growth Factor A

SCOPe Domain Sequences for d1tzhw_:

Sequence; same for both SEQRES and ATOM records:

>d1tzhw_ g.17.1.1 (W:) Vascular endothelial growth factor, VEGF {Human (Homo sapiens) [TaxId: 9606]}
vvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvptee
snitmqimrikphqgqhigemsflqhnkcecrpk

Timeline for d1tzhw_:

• d1tzhw_ first appeared in SCOP 1.69
  
• d1tzhw_ appears in SCOPe 2.04
  
• d1tzhw_ appears in SCOPe 2.06
  
• d1tzhw_ appears in the current release, SCOPe 2.08