SCOPe 2.06: Domain d1tk0a2: 1tk0 A:211-704

Lineage for d1tk0a2 (1tk0 A:211-704)

1. Root: SCOPe 2.06

2. Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)

6. Protein T7 phage DNA polymerase [56678] (1 species)

7. Species Bacteriophage T7 [TaxId:10760] [56679] (17 PDB entries)
   Uniprot P00581

8. Domain d1tk0a2: 1tk0 A:211-704 [107064]
   Other proteins in same PDB: d1tk0a1, d1tk0b_
   protein/DNA complex; complexed with 1pe, dct, mes, mg, so4

Details for d1tk0a2

PDB Entry: 1tk0, 2.3 Å

PDB Description: t7 dna polymerase ternary complex with 8 oxo guanosine and ddctp at the insertion site

PDB Compounds: (A:) DNA polymerase

SCOPe Domain Sequences for d1tk0a2:

Sequence, based on SEQRES records:

>d1tk0a2 e.8.1.1 (A:211-704) T7 phage DNA polymerase {Bacteriophage T7 [TaxId: 10760]}
leavdiehraawllakqerngfpfdtkaieelyvelaarrsellrkltetfgswyqpkgg
temfchprtgkplpkypriktpkvggifkkpknkaqregrepceldtreyvagapytpve
hvvfnpssrdhiqkklqeagwvptkytdkgapvvddevlegvrvddpekqaaidlikeyl
miqkrigqsaegdkawlryvaedgkihgsvnpngavtgrathafpnlaqipgvrspygeq
craafgaehhldgitgkpwvqagidasglelrclahfmarfdngeyaheilngdihtknq
iaaelptrdnaktfiygflygagdekigqivgagkergkelkkkflentpaiaalresiq
qtlvessqwvageqqvkwkrrwikgldgrkvhvrsphaalntllqsagalicklwiikte
emlvekglkhgwdgdfaymawvhdeiqvgcrteeiaqvvietaqeamrwvgdhwnfrcll
dtegkmgpnwaich

Sequence, based on observed residues (ATOM records):

>d1tk0a2 e.8.1.1 (A:211-704) T7 phage DNA polymerase {Bacteriophage T7 [TaxId: 10760]}
leavdiehraawllakqerngfpfdtkaieelyvelaarrsellrkltetfgswyqpkgg
temfchprtgkplpkypriktpkvggifkkpegrepceldtreyvagapytpvehvvfnp
ssrdhiqkklqeagwvptkytdkgapvvddevlegvrvddpekqaaidlikeylmiqkri
gqsaegdkawlryvaedgkihgsvnpngavtgrathafpnlaqipgvrspygeqcraafg
aehhldgitgkpwvqagidasglelrclahfmarfdngeyaheilngdihtknqiaaelp
trdnaktfiygflygagdekigqivgagkergkelkkkflentpaiaalresiqqtlves
sqqvkwkrrwikgldgrkvhvrsphaalntllqsagalicklwiikteemlvekglkhgw
dgdfaymawvhdeiqvgcrteeiaqvvietaqeamrwvgdhwnfrclldtegkmgpnwai
ch

Timeline for d1tk0a2:

• d1tk0a2 first appeared in SCOP 1.69
  
• d1tk0a2 appears in SCOPe 2.05
  
• d1tk0a2 appears in SCOPe 2.07
  
• d1tk0a2 appears in the current release, SCOPe 2.08