SCOPe 2.05: Domain d1tfza2: 1tfz A:196-408

Lineage for d1tfza2 (1tfz A:196-408)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
   beta-alpha-beta(3); 2 layers: alpha/beta

4. Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families)

5. Family d.32.1.3: Extradiol dioxygenases [54602] (5 proteins)
   duplication: consists of 2 similar domains with 2 repeats in each
   Similar to the Methylmalonyl-CoA epimerase dimer

6. Protein 4-hydroxyphenylpyruvate dioxygenase, HppD [54608] (6 species)

7. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [110877] (4 PDB entries)
   Uniprot P93836 33-428 ! Uniprot P93836 63-459

8. Domain d1tfza2: 1tfz A:196-408 [106887]
   complexed with 869, fe

Details for d1tfza2

PDB Entry: 1tfz, 1.8 Å

PDB Description: structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and mammalian 4- hydroxyphenylpyruvate dioxygenases

PDB Compounds: (A:) 4-hydroxyphenylpyruvate dioxygenase

SCOPe Domain Sequences for d1tfza2:

Sequence, based on SEQRES records:

>d1tfza2 d.32.1.3 (A:196-408) 4-hydroxyphenylpyruvate dioxygenase, HppD {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}
ldygirrldhavgnvpelgpaltyvagftgfhqfaeftaddvgtaesglnsavlasndem
vllpinepvhgtkrksqiqtylehnegaglqhlalmsedifrtlremrkrssiggfdfmp
sppptyyqnlkkrvgdvlsddqikeceelgilvdrddqgtllqiftkplgdrptifieii
qrvgcmmkdeegkayqsggcggfgkgnfselfk

Sequence, based on observed residues (ATOM records):

>d1tfza2 d.32.1.3 (A:196-408) 4-hydroxyphenylpyruvate dioxygenase, HppD {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}
ldygirrldhavgnvpelgpaltyvagftgfhqfasglnsavlasndemvllpinepvhg
ksqiqtylehnegaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrv
gdvlsddqikeceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmqsggcggf
gkgnfselfk

Timeline for d1tfza2:

• d1tfza2 first appeared in SCOP 1.69
  
• d1tfza2 appears in SCOPe 2.04
  
• d1tfza2 appears in SCOPe 2.06
  
• d1tfza2 appears in the current release, SCOPe 2.08