SCOPe 2.02: Domain d1tedd_: 1ted D:

Lineage for d1tedd_ (1ted D:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (3 families)

5. Family c.95.1.2: Chalcone synthase-like [53914] (8 proteins)

6. Protein Polyketide synthase PKS18 [110758] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [110759] (2 PDB entries)
   Uniprot Q79FQ0

8. Domain d1tedd_: 1ted D: [106810]
   complexed with myr

Details for d1tedd_

PDB Entry: 1ted, 2.25 Å

PDB Description: Crystal structure of a type III polyketide synthase PKS18 from Mycobacterium tuberculosis

PDB Compounds: (D:) pks18

SCOPe Domain Sequences for d1tedd_:

Sequence, based on SEQRES records:

>d1tedd_ c.95.1.2 (D:) Polyketide synthase PKS18 {Mycobacterium tuberculosis [TaxId: 1773]}
tvavieglatgtprrvvnqsdaadrvaelfldpgqreriprvyqksrittrrmavdplda
kfdvfrrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapg
vdvaivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielcsvnav
faddindvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgivlgvnh
ngitcelsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvrslgis
aelaaqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtvegmlfdi
irr

Sequence, based on observed residues (ATOM records):

>d1tedd_ c.95.1.2 (D:) Polyketide synthase PKS18 {Mycobacterium tuberculosis [TaxId: 1773]}
tvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmavdpldakfdv
frrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapgvdva
ivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielcsvnavfadd
indvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgivlgvnhngit
celsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvrslgisaela
aqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtvegmlfdiirr

Timeline for d1tedd_:

• d1tedd_ first appeared in SCOP 1.69
  
• d1tedd_ appears in SCOPe 2.01
  
• d1tedd_ last appears in SCOPe 2.03