SCOPe 2.01: Domain d1t39a2: 1t39 A:6-91

Lineage for d1t39a2 (1t39 A:6-91)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.7: Methylated DNA-protein cysteine methyltransferase domain [53155] (1 family)

5. Family c.55.7.1: Methylated DNA-protein cysteine methyltransferase domain [53156] (2 proteins)

6. Protein O6-alkylguanine-DNA alkyltransferase [53159] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53160] (7 PDB entries)
   Uniprot P16455 6-176

8. Domain d1t39a2: 1t39 A:6-91 [106336]
   Other proteins in same PDB: d1t39a1, d1t39b1
   protein/DNA complex

Details for d1t39a2

PDB Entry: 1t39, 3.3 Å

PDB Description: human o6-alkylguanine-dna alkyltransferase covalently crosslinked to dna

PDB Compounds: (A:) methylated-DNA--protein-cysteine methyltransferase

SCOPe Domain Sequences for d1t39a2:

Sequence, based on SEQRES records:

>d1t39a2 c.55.7.1 (A:6-91) O6-alkylguanine-DNA alkyltransferase {Human (Homo sapiens) [TaxId: 9606]}
emkrttldsplgklelsgceqglheikllgkgtsaadavevpapaavlggpeplmqctaw
lnayfhqpeaieefpvpalhhpvfqq

Sequence, based on observed residues (ATOM records):

>d1t39a2 c.55.7.1 (A:6-91) O6-alkylguanine-DNA alkyltransferase {Human (Homo sapiens) [TaxId: 9606]}
emkrttldsplgklelsgceqglheikllgpeplmqctawlnayfhqpeaieefpvpalh
hpvfqq

Timeline for d1t39a2:

• d1t39a2 first appeared in SCOP 1.69
  
• d1t39a2 appears in SCOP 1.75
  
• d1t39a2 appears in SCOPe 2.02
  
• d1t39a2 appears in the current release, SCOPe 2.08