SCOPe 2.03: Domain d1smib_: 1smi B:

Lineage for d1smib_ (1smi B:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Cytochrome P450 bm-3 [48268] (1 species)

7. Species Bacillus megaterium [TaxId:1404] [48269] (58 PDB entries)
   Uniprot P14779

8. Domain d1smib_: 1smi B: [105759]
   complexed with hem; mutant

Details for d1smib_

PDB Entry: 1smi, 2 Å

PDB Description: a single mutation of p450 bm3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme

PDB Compounds: (B:) bifunctional p-450:nadph-p450 reductase

SCOPe Domain Sequences for d1smib_:

Sequence, based on SEQRES records:

>d1smib_ a.104.1.1 (B:) Cytochrome P450 bm-3 {Bacillus megaterium [TaxId: 1404]}
ikempqpktfgelknlpllntdkpvqalmkiadelgeifkfeapgrvtrylssqrlikea
cdesrfdknlsqalkfvrdfagdglftswtheknwkkahnillpsfsqqamkgyhammvd
iavqlvqkwerlnadehievpedmtrltldtiglcgfnyrfnsfyrdqphpfitsmvral
deamnklqranpddpaydenkrqfqedikvmndlvdkiiadrkasgeqsddllthmlngk
dpetgeplddeniryqiitflieghettsgllsfalyflvknphvlqkaaeeaarvlvdp
vpsykqvkqlkyvgmvlnealrlwptapafslyakedtvlggeyplekgdelmvlipqlh
rdktiwgddveefrperfenpsaipqhafkpfgngqracigqqfalheatlvlgmmlkhf
dfedhtnyeldiketltlkpegfvvkakskkiplggi

Sequence, based on observed residues (ATOM records):

>d1smib_ a.104.1.1 (B:) Cytochrome P450 bm-3 {Bacillus megaterium [TaxId: 1404]}
ikempqpktfgelknlpllntdkpvqalmkiadelgeifkfeapgrvtrylssqrlikea
cdesrfdknlsqalkfvrdfagdglftswtheknwkkahnillpsfsqqamkgyhammvd
iavqlvqkwerlnadehievpedmtrltldtiglcgfnyrfnsfyrdqphpfitsmvral
deamnklqranpddpaydenkrqfqedikvmndlvdkiiadrkasqsddllthmlngkdp
etgeplddeniryqiitflieghettsgllsfalyflvknphvlqkaaeeaarvlvdpvp
sykqvkqlkyvgmvlnealrlwptapafslyakedtvlggeyplekgdelmvlipqlhrd
ktiwgddveefrperfenpsaipqhafkpfgngqracigqqfalheatlvlgmmlkhfdf
edhtnyeldiketltlkpegfvvkakskkiplggi

Timeline for d1smib_:

• d1smib_ first appeared in SCOP 1.69
  
• d1smib_ appears in SCOPe 2.02
  
• d1smib_ appears in SCOPe 2.04
  
• d1smib_ appears in the current release, SCOPe 2.08