Lineage for d1sk6b_ (1sk6 B:)

  1. Root: SCOP 1.69
  2. 517079Class e: Multi-domain proteins (alpha and beta) [56572] (46 folds)
  3. 518934Fold e.41: Adenylylcyclase toxin (the edema factor) [81299] (1 superfamily)
    3 domains: (1&2) alpha+beta, with domain 2 being inserted in domain 1; (3) all-alpha
  4. 518935Superfamily e.41.1: Adenylylcyclase toxin (the edema factor) [81298] (1 family) (S)
    Domain 1 has topological and active site similarity to the Nucleotidyltransferases (eg. 1kny N-domain); domain 3 binds calmodulin
  5. 518936Family e.41.1.1: Adenylylcyclase toxin (the edema factor) [69887] (1 protein)
    decorated with many insertions and the C-terminal domain
  6. 518937Protein Adenylylcyclase toxin (the edema factor) [69888] (1 species)
  7. 518938Species Bacillus anthracis [TaxId:1392] [69889] (7 PDB entries)
  8. 518950Domain d1sk6b_: 1sk6 B: [105666]
    Other proteins in same PDB: d1sk6d_, d1sk6e_, d1sk6f_

Details for d1sk6b_

PDB Entry: 1sk6 (more details), 3.2 Å

PDB Description: Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate

SCOP Domain Sequences for d1sk6b_:

Sequence, based on SEQRES records: (download)

>d1sk6b_ e.41.1.1 (B:) Adenylylcyclase toxin (the edema factor) {Bacillus anthracis}
dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtnll
ikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdnei
fiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkak
intiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhifs
qekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksnief
kllykqlnftenetdnfevfqkiid

Sequence, based on observed residues (ATOM records): (download)

>d1sk6b_ e.41.1.1 (B:) Adenylylcyclase toxin (the edema factor) {Bacillus anthracis}
dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnekqkgvtnllik
ygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdneifi
inpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkakin
tipsdyynsanhifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritn
qvqlllthqkllykqlnftenetdnfevfqkiid

SCOP Domain Coordinates for d1sk6b_:

Click to download the PDB-style file with coordinates for d1sk6b_.
(The format of our PDB-style files is described here.)

Timeline for d1sk6b_: