SCOP 1.71: Domain d1sdva_: 1sdv A:

Lineage for d1sdva_ (1sdv A:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (179 PDB entries)

8. Domain d1sdva_: 1sdv A: [105446]

Details for d1sdva_

PDB Entry: 1sdv, 1.4 Å

PDB Description: Crystal structures of HIV protease V82A and L90M mutants reveal changes in indinavir binding site.

SCOP Domain Sequences for d1sdva_:

Sequence; same for both SEQRES and ATOM records:

>d1sdva_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpaniigrnlltqigatlnf

Timeline for d1sdva_:

• d1sdva_ first appeared in SCOP 1.69
  
• d1sdva_ appears in SCOP 1.73
  
• d1sdva_ appears in the current release, SCOPe 2.08