Lineage for d1s3kh2 (1s3k H:120-219)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 654118Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 655111Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)
  7. 655115Species Human (Homo sapiens) [TaxId:9606] [88575] (150 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
  8. 655341Domain d1s3kh2: 1s3k H:120-219 [105238]
    Other proteins in same PDB: d1s3kh1, d1s3kl1, d1s3kl2
    MQ NA P01857 # artificial chimera
    complexed with fuc, gal, gol, nag

Details for d1s3kh2

PDB Entry: 1s3k (more details), 1.9 Å

PDB Description: crystal structure of a humanized fab (hu3s193) in complex with the lewis y tetrasaccharide
PDB Compounds: (H:) HU3S193 Fab fragment, heavy chain

SCOP Domain Sequences for d1s3kh2:

Sequence, based on SEQRES records: (download)

>d1s3kh2 b.1.1.2 (H:120-219) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapsskstsggtaalgclvkdyfpqpvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

Sequence, based on observed residues (ATOM records): (download)

>d1s3kh2 b.1.1.2 (H:120-219) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapgtaalgclvkdyfpqpvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

SCOP Domain Coordinates for d1s3kh2:

Click to download the PDB-style file with coordinates for d1s3kh2.
(The format of our PDB-style files is described here.)

Timeline for d1s3kh2:

View in 3D
Domains from same chain:
(mouse over for more information)
d1s3kh1