Lineage for d1s3kh1 (1s3k H:1-119)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 546419Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 546420Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)
  6. 547289Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 547290Species Engineered (including hybrid species) [88533] (52 PDB entries)
  8. 547359Domain d1s3kh1: 1s3k H:1-119 [105237]
    Other proteins in same PDB: d1s3kh2, d1s3kl2
    MQ NA P01857 # artificial chimera
    complexed with fuc, gal, gol, nag

Details for d1s3kh1

PDB Entry: 1s3k (more details), 1.9 Å

PDB Description: crystal structure of a humanized fab (hu3s193) in complex with the lewis y tetrasaccharide

SCOP Domain Sequences for d1s3kh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1s3kh1 b.1.1.1 (H:1-119) Immunoglobulin light chain kappa variable domain, VL-kappa {Engineered (including hybrid species)}

SCOP Domain Coordinates for d1s3kh1:

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Timeline for d1s3kh1:

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