SCOP 1.71: Domain d1o5dh_: 1o5d H:

Lineage for d1o5dh_ (1o5d H:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (10 PDB entries)

8. Domain d1o5dh_: 1o5d H: [103880]
   Other proteins in same PDB: d1o5dl1, d1o5dl2, d1o5dt1, d1o5dt2
   complexed with cr9; mutant

Details for d1o5dh_

PDB Entry: 1o5d, 2.05 Å

PDB Description: dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa)

SCOP Domain Sequences for d1o5dh_:

Sequence; same for both SEQRES and ATOM records:

>d1o5dh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens)}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d1o5dh_:

• d1o5dh_ first appeared in SCOP 1.69
  
• d1o5dh_ appears in SCOP 1.73
  
• d1o5dh_ appears in the current release, SCOPe 2.08