Lineage for Protein: Angiotensin converting enzyme 2, ACE2

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1917420Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 1917421Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 1917605Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 1917606Protein Angiotensin converting enzyme 2, ACE2 [103125] (2 species)

Species:

  1. 1917607Human (Homo sapiens) [TaxId:9606] [103126] (5 PDB entries)
    1. Domain for 1r42:
      • 1917614Domain d1r42a_: 1r42 A: [96968]
        complexed with collectrin homology domain (disordered segments), chains B, C, D and E
        complexed with cl, nag, zn
    2. Domain for 1r4l:
      • 1917615Domain d1r4la_: 1r4l A: [96998]
        complexed with collectrin homology domain (disordered segments), chains B, C, D and E
        complexed with cl, nag, xx5, zn
    3. Domains for 2ajf:
      1. 1917612Domain d2ajfa_: 2ajf A: [126882]
        Other proteins in same PDB: d2ajfe1, d2ajff_
        automated match to d1r42a_
        complexed with cl, nag, zn
      2. 1917613Domain d2ajfb_: 2ajf B: [126883]
        Other proteins in same PDB: d2ajfe1, d2ajff_
        automated match to d1r42a_
        complexed with cl, nag, zn
    4. Domains for 3sci:
      1. 1917608Domain d3scia_: 3sci A: [200605]
        Other proteins in same PDB: d3scie_, d3scif_
        automated match to d3scib_
        complexed with cl, zn
      2. 1917609Domain d3scib_: 3sci B: [196047]
        Other proteins in same PDB: d3scie_, d3scif_
        automated match to d2ajfa_
        complexed with cl, zn
    5. Domains for 3scj:
      1. 1917610Domain d3scja_: 3scj A: [249343]
        Other proteins in same PDB: d3scje_, d3scjf_
        automated match to d3d0ga_
        complexed with cl, zn
      2. 1917611Domain d3scjb_: 3scj B: [249344]
        Other proteins in same PDB: d3scje_, d3scjf_
        automated match to d3d0ga_
        complexed with cl, zn
  2. 1917616Paguma larvata [188486] (5 PDB entries)
    1. Domains for 3d0g:
      1. 1917617Domain d3d0ga_: 3d0g A: [161632]
        Other proteins in same PDB: d3d0ge_, d3d0gf_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
      2. 1917618Domain d3d0gb_: 3d0g B: [161633]
        Other proteins in same PDB: d3d0ge_, d3d0gf_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
    2. Domains for 3d0h:
      1. 1917621Domain d3d0ha_: 3d0h A: [245597]
        Other proteins in same PDB: d3d0he_, d3d0hf_
        automated match to d3d0ga_
        complexed with cl, nag, ndg, zn
      2. 1917622Domain d3d0hb_: 3d0h B: [245598]
        Other proteins in same PDB: d3d0he_, d3d0hf_
        automated match to d3d0ga_
        complexed with cl, nag, ndg, zn
    3. Domains for 3d0i:
      1. 1917619Domain d3d0ia_: 3d0i A: [173600]
        Other proteins in same PDB: d3d0ie_, d3d0if_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
      2. 1917620Domain d3d0ib_: 3d0i B: [173601]
        Other proteins in same PDB: d3d0ie_, d3d0if_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
    4. Domains for 3sck:
      1. 1917625Domain d3scka_: 3sck A: [249347]
        Other proteins in same PDB: d3scke_, d3sckf_
        automated match to d3d0ga_
        complexed with cl, zn
      2. 1917626Domain d3sckb_: 3sck B: [249348]
        Other proteins in same PDB: d3scke_, d3sckf_
        automated match to d3d0ga_
        complexed with cl, zn
    5. Domains for 3scl:
      1. 1917623Domain d3scla_: 3scl A: [249351]
        Other proteins in same PDB: d3scle_, d3sclf_
        automated match to d3d0ga_
        complexed with cl, zn
      2. 1917624Domain d3sclb_: 3scl B: [249352]
        Other proteins in same PDB: d3scle_, d3sclf_
        automated match to d3d0ga_
        complexed with cl, zn

More info for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like

Timeline for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like: