Lineage for Family d.14.1.8: Hsp90 middle domain

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.14: Ribosomal protein S5 domain 2-like [54210] (1 superfamily) core: beta(3)-alpha-beta-alpha; 2 layers: alpha/beta; left-handed crossover

4. Superfamily d.14.1: Ribosomal protein S5 domain 2-like [54211] (11 families)

5. Family d.14.1.8: Hsp90 middle domain [102755] (1 protein) related to the DNA gyrase/MutL family; contains extra C-terminal alpha/beta subdomain