SCOPe 2.01: Species: Human (Homo sapiens), cluster 4 [TaxId: 9606]

Lineage for Species: Human (Homo sapiens), cluster 4 [TaxId: 9606]

Root: SCOPe 2.01
Class b: All beta proteins [48724] (174 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (5 families)
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

Species Human (Homo sapiens), cluster 4 [TaxId:9606] [101505] (3 PDB entries)

PDB entries in Species: Human (Homo sapiens), cluster 4 [TaxId: 9606]:

Domain(s) for 1q1j:
1. Domain d1q1jh1: 1q1j H:1-113 [95581]
  Other proteins in same PDB: d1q1jh2, d1q1ji2, d1q1jl1, d1q1jl2, d1q1jm1, d1q1jm2
  part of anti HIV-1 Fab 447-52d
2. Domain d1q1ji1: 1q1j I:1-113 [95583]
  Other proteins in same PDB: d1q1jh2, d1q1ji2, d1q1jl1, d1q1jl2, d1q1jm1, d1q1jm2
  part of anti HIV-1 Fab 447-52d
Domain(s) for 2b4c:
- Domain d2b4ch1: 2b4c H:4-113 [127822]
  Other proteins in same PDB: d2b4cc1, d2b4cc2, d2b4cg1, d2b4ch2, d2b4cl1, d2b4cl2
  automatically matched to d1q1jh1
  complexed with nag, ndg, so4, xyl
Domain(s) for 3c2a:
1. Domain d3c2ah1: 3c2a H:1-113 [155872]
  Other proteins in same PDB: d3c2ah2, d3c2ai2
  automatically matched to d1q1jh1
2. Domain d3c2ai1: 3c2a I:1-113 [155874]
  Other proteins in same PDB: d3c2ah2, d3c2ai2
  automatically matched to d1q1jh1

More info for Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH

Timeline for Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH:

Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH first appeared in SCOP 1.67
Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH appears in SCOP 1.75
Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH appears in SCOPe 2.02
Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH appears in the current release, SCOPe 2.08