SCOP 1.69: Family a.4.5.39: Penicillinase repressor

Lineage for Family a.4.5.39: Penicillinase repressor

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (13 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (55 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.39: Penicillinase repressor [101016] (2 proteins)
   homologous to the MarR-like family in the DNA-binding region but has a different dimerisation subdomain

Proteins:

1. Methicillin resistance regulatory protein MecI [101017] (1 species)

   • Species Staphyloccocus aureus [101018] (4 PDB entries)

2. Penicillinase repressor BlaI [101019] (2 species)

   1. Species Bacillus licheniformis [TaxId:1402] [101020] (1 PDB entry)

   2. Species Staphylococcus aureus [TaxId:1280] [109666] (1 PDB entry)

More info for Family a.4.5.39: Penicillinase repressor

Timeline for Family a.4.5.39: Penicillinase repressor:

• Family a.4.5.39: Penicillinase repressor first appeared in SCOP 1.67
  
• Family a.4.5.39: Penicillinase repressor appears in SCOP 1.71
  
• Family a.4.5.39: Penicillinase repressor appears in the current release, SCOPe 2.08