Lineage for Family c.47.1.13: DsbA-like

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 395822Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
    core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
  4. 395823Superfamily c.47.1: Thioredoxin-like [52833] (14 families) (S)
  5. 396590Family c.47.1.13: DsbA-like [100953] (2 proteins)
    contains an all-alpha subdomain insertion

Proteins:

  1. 396591Disulfide-bond formation facilitator (DsbA) [100954] (2 species)
    the insert subdomain is a 4-helical bundle
    1. 396592Species Escherichia coli [TaxId:562] [100955] (12 PDB entries)
    2. 396617Species Vibrio cholerae [TaxId:666] [100956] (1 PDB entry)
      TcpG, periplasmic enzyme required for the maturation of secreted virulence factors
  2. 396619Mitochondrial class kappa glutathione S-transferase [102437] (1 species)
    contains larger and less compact insertion in the common fold than DsbA

More info for Family c.47.1.13: DsbA-like

Timeline for Family c.47.1.13: DsbA-like: