Welcome to SCOPe!

The SCOPe website provides integrated access to data found in all releases of the SCOP and Astral databases that feature stable identifiers.


  • 2017-12-22: SCOPe 2.07-stable is being prepared for release in Feb 2018. The new release features manual classification of domains from many larger structures, including the spliceosome, proteasome, and RNA polymerase I, and many other Pfam families not previously classified in SCOP. We have identified dozens of new superfamilies that will be included in the upcoming release.
  • 2017-09-01: We are still without funding, but shutdown has been postponed for a year. More details are here.
  • 2016-11-30: We published a paper on new features in SCOPe [PDF].
  • 2015-09-22: We published a paper about how SCOP and SCOPe have been used in recent studies [PDF].

Classes in SCOP 1.59:

  1. 93448a: All alpha proteins [46456] (151 folds)
  2. 101936b: All beta proteins [48724] (110 folds)
  3. 115903c: Alpha and beta proteins (a/b) [51349] (113 folds)
  4. 128814d: Alpha and beta proteins (a+b) [53931] (208 folds)
  5. 140364e: Multi-domain proteins (alpha and beta) [56572] (34 folds)
  6. 141686f: Membrane and cell surface proteins and peptides [56835] (12 folds)
  7. 142453g: Small proteins [56992] (58 folds)
  8. 145365h: Coiled coil proteins [57942] (5 folds)
  9. 146111i: Low resolution protein structures [58117] (16 folds)
  10. 146832j: Peptides [58231] (92 folds)
  11. 147892k: Designed proteins [58788] (31 folds)