Lineage for d4tpwa_ (4tpw A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2962641Fold d.86: eIF4e-like [55417] (1 superfamily)
    beta(2)-alpha-beta(2)-alpha-beta(2)-alpha-beta-2; 2 layers: alpha/beta; antiparallel sheet: 21356478
  4. 2962642Superfamily d.86.1: eIF4e-like [55418] (3 families) (S)
  5. 2962643Family d.86.1.1: Translation initiation factor eIF4e [55419] (1 protein)
    automatically mapped to Pfam PF01652
  6. 2962644Protein Translation initiation factor eIF4e [55420] (3 species)
    messenger RNA 5' cap-binding protein
  7. 2962648Species Human (Homo sapiens) [TaxId:9606] [160542] (16 PDB entries)
  8. 2962651Domain d4tpwa_: 4tpw A: [259026]
    automated match to d1ipca_
    complexed with 33r, mes, mgp

Details for d4tpwa_

PDB Entry: 4tpw (more details), 1.5 Å

PDB Description: the co-complex structure of the translation initiation factor eif4e with the inhibitor 4egi-1 reveals an allosteric mechanism for dissociating eif4g
PDB Compounds: (A:) eukaryotic translation initiation factor 4e

SCOPe Domain Sequences for d4tpwa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4tpwa_ d.86.1.1 (A:) Translation initiation factor eIF4e {Human (Homo sapiens) [TaxId: 9606]}
hyikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdys
lfkdgiepmwedeknkrggrwlitlnkqqrrsdldrfwletllcligesfddysddvcga
vvnvrakgdkiaiwttecenreavthigrvykerlglppkivigyqshadtatksgsttk
nrfvv

SCOPe Domain Coordinates for d4tpwa_:

Click to download the PDB-style file with coordinates for d4tpwa_.
(The format of our PDB-style files is described here.)

Timeline for d4tpwa_:

2962651
d4tpwa_ in context of PDB
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d4tpwb_