Lineage for d4f45a_ (4f45 A:)
- Root: SCOPe 2.04
Class c: Alpha and beta proteins (a/b) [51349] (148 folds) 
Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
Superfamily c.23.14: N-(deoxy)ribosyltransferase-like [52309] (4 families) 
there are similar active site architectures as well as the catalytic mechanisms of functionally characterised membersFamily c.23.14.3: ADP ribosyl cyclase-like [56630] (3 proteins)
contains extra N-terminal all-alpha subdomain
automatically mapped to Pfam PF02267Protein ADP ribosyl cyclase [56631] (4 species) Species Human (Homo sapiens) [TaxId:9606] [159490] (35 PDB entries)
Uniprot P28907 45-291
Domain d4f45a_: 4f45 A: [196738]
automated match to d2o3ta_
complexed with dn4; mutant
Details for d4f45a_
PDB Entry: 4f45 (more details), 2.1 Å
PDB Description: Crystal structure of human CD38 E226Q mutant in complex with NAADP
PDB Compounds: (A:) ADP-ribosyl cyclase 1SCOPe Domain Sequences for d4f45a_:
Sequence, based on SEQRES records: (download)
>d4f45a_ c.23.14.3 (A:) ADP ribosyl cyclase {Human (Homo sapiens) [TaxId: 9606]}
efwrqtwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcdite
edyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgef
dtskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfg
svqvhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdk
flqcvknpedssc
Sequence, based on observed residues (ATOM records): (download)
>d4f45a_ c.23.14.3 (A:) ADP ribosyl cyclase {Human (Homo sapiens) [TaxId: 9606]}
efwrqtwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcdite
edyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgef
dtskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfg
svqvhnlqpekvqtleawvihggrdlcqdptikelesiiskrniqfsckniyrpdkflqc
vknpedssc
SCOPe Domain Coordinates for d4f45a_:
Click to download the PDB-style file with coordinates for d4f45a_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d4f45a_:
- d4f45a_ first appeared in SCOPe 2.02
- d4f45a_ appears in SCOPe 2.03
- d4f45a_ appears in SCOPe 2.05
- d4f45a_ appears in the current release, SCOPe 2.08, called d4f45a1
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