Lineage for d3scib_ (3sci B:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1917420Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 1917421Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 1917605Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 1917606Protein Angiotensin converting enzyme 2, ACE2 [103125] (2 species)
  7. 1917607Species Human (Homo sapiens) [TaxId:9606] [103126] (5 PDB entries)
  8. 1917609Domain d3scib_: 3sci B: [196047]
    Other proteins in same PDB: d3scie_, d3scif_
    automated match to d2ajfa_
    complexed with cl, zn

Details for d3scib_

PDB Entry: 3sci (more details), 2.9 Å

PDB Description: crystal structure of spike protein receptor-binding domain from a predicted sars coronavirus human strain complexed with human receptor ace2
PDB Compounds: (B:) Angiotensin-converting enzyme 2

SCOPe Domain Sequences for d3scib_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3scib_ d.92.1.5 (B:) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens) [TaxId: 9606]}
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

SCOPe Domain Coordinates for d3scib_:

Click to download the PDB-style file with coordinates for d3scib_.
(The format of our PDB-style files is described here.)

Timeline for d3scib_: