Lineage for d3scia_ (3sci A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2528985Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 2528986Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 2529230Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 2529231Protein Angiotensin converting enzyme 2, ACE2 [103125] (2 species)
  7. 2529232Species Human (Homo sapiens) [TaxId:9606] [103126] (20 PDB entries)
  8. 2529233Domain d3scia_: 3sci A: [200605]
    Other proteins in same PDB: d3scie_, d3scif_
    automated match to d3scib_
    complexed with cl, zn

Details for d3scia_

PDB Entry: 3sci (more details), 2.9 Å

PDB Description: crystal structure of spike protein receptor-binding domain from a predicted sars coronavirus human strain complexed with human receptor ace2
PDB Compounds: (A:) Angiotensin-converting enzyme 2

SCOPe Domain Sequences for d3scia_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3scia_ d.92.1.5 (A:) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens) [TaxId: 9606]}
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

SCOPe Domain Coordinates for d3scia_:

Click to download the PDB-style file with coordinates for d3scia_.
(The format of our PDB-style files is described here.)

Timeline for d3scia_: