Lineage for d3nf3a_ (3nf3 A:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1423492Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 1423493Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 1423777Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)
  6. 1423778Protein Botulinum neurotoxin [55513] (4 species)
  7. 1423779Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (23 PDB entries)
    Uniprot P10845 1-419
  8. 1423800Domain d3nf3a_: 3nf3 A: [182217]
    automated match to d1xtga_
    complexed with ni, zn

Details for d3nf3a_

PDB Entry: 3nf3 (more details), 2.4 Å

PDB Description: Crystal structure of BoNT/A LC with JTH-NB-7239 peptide
PDB Compounds: (A:) BoNT/A

SCOPe Domain Sequences for d3nf3a_:

Sequence, based on SEQRES records: (download)

>d3nf3a_ d.92.1.7 (A:) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mpfvnkqfnykdpvngvdiayikipnagqmqpvkafkihnkiwviperdtftnpeegdln
pppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwgg
stidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngy
gstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpn
rvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnka
ksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkv
lnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklk

Sequence, based on observed residues (ATOM records): (download)

>d3nf3a_ d.92.1.7 (A:) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mpfvnkqfnykdpvngvdiayikipnqmqpvkafkihnkiwviperdtftnpeegdlppp
eakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggsti
dtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngygst
qyirfspdftfgfeegkfatdpavtlahelihaghrlygiainpnrvfkvnlevsfeelr
tfgghdakfidslqenefrlyyynkfkdiastlnkaksivgtaslqymknvfkekyllse
dtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktylnfdkavfkinivpkvnyt
iydgfnlrntnlaanfngqnteinnmnftklk

SCOPe Domain Coordinates for d3nf3a_:

Click to download the PDB-style file with coordinates for d3nf3a_.
(The format of our PDB-style files is described here.)

Timeline for d3nf3a_: