Lineage for d3b2ra_ (3b2r A:)

  1. Root: SCOPe 2.05
  2. 1715731Class a: All alpha proteins [46456] (286 folds)
  3. 1753307Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 1753308Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 1753393Family a.211.1.2: PDEase [48548] (7 proteins)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 1753586Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species)
  7. 1753587Species Human (Homo sapiens) [TaxId:9606] [101440] (18 PDB entries)
    Uniprot O76074 534-860
  8. 1753600Domain d3b2ra_: 3b2r A: [154768]
    automated match to d1rkpa_
    complexed with vdn

Details for d3b2ra_

PDB Entry: 3b2r (more details), 2.07 Å

PDB Description: Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
PDB Compounds: (A:) cGMP-specific 3',5'-cyclic phosphodiesterase

SCOPe Domain Sequences for d3b2ra_:

Sequence, based on SEQRES records: (download)

>d3b2ra_ a.211.1.2 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens) [TaxId: 9606]}
gshmeetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqm
khevlcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaa
lshdldhrgvnnsyiqrsehplaqlychsimehhhfdqclmilnspgnqilsglsieeyk
ttlkiikqailatdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitk
pwpiqqriaelvateffdqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlye
althvsedcfplldgcrknrqkwqalaeqq

Sequence, based on observed residues (ATOM records): (download)

>d3b2ra_ a.211.1.2 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens) [TaxId: 9606]}
gshmeetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqm
khevlcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaa
lshdldhrgvchsimehhhfdqclmilnspgnqilsglsieeykttlkiikqailatdla
lyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqqriaelvatef
fdqgdkknkipsmqvgfidaiclqlyealthvsedcfplldgcrknrqkwqalaeqq

SCOPe Domain Coordinates for d3b2ra_:

Click to download the PDB-style file with coordinates for d3b2ra_.
(The format of our PDB-style files is described here.)

Timeline for d3b2ra_: