Lineage for d2q7oe_ (2q7o E:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1860688Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 1860705Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families) (S)
    complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8
  5. 1860706Family c.56.2.1: Purine and uridine phosphorylases [53168] (7 proteins)
  6. 1860816Protein Purine nucleoside phosphorylase, PNP [53169] (12 species)
  7. 1860994Species Human (Homo sapiens) [TaxId:9606] [53170] (29 PDB entries)
    Uniprot P00491
  8. 1861029Domain d2q7oe_: 2q7o E: [150096]
    automated match to d1ulaa_
    complexed with imh, po4

Details for d2q7oe_

PDB Entry: 2q7o (more details), 2.9 Å

PDB Description: structure of human purine nucleoside phosphorylase in complex with l- immucillin-h
PDB Compounds: (E:) purine nucleoside phosphorylase

SCOPe Domain Sequences for d2q7oe_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2q7oe_ c.56.2.1 (E:) Purine nucleoside phosphorylase, PNP {Human (Homo sapiens) [TaxId: 9606]}
mengytyedykntaewllshtkhrpqvaiicgsglggltdkltqaqifdyseipnfprst
vpghagrlvfgflngracvmmqgrfhmyegyplwkvtfpvrvfhllgvdtlvvtnaaggl
npkfevgdimlirdhinlpgfsgqnplrgpnderfgdrfpamsdaydrtmrqralstwkq
mgeqrelqegtyvmvagpsfetvaecrvlqklgadavgmstvpevivarhcglrvfgfsl
itnkvimdyeslekanheevlaagkqaaqkleqfvsilmasipl

SCOPe Domain Coordinates for d2q7oe_:

Click to download the PDB-style file with coordinates for d2q7oe_.
(The format of our PDB-style files is described here.)

Timeline for d2q7oe_: