Lineage for d2gs6a_ (2gs6 A:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1220711Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)
    PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase
  7. 1220712Species Human (Homo sapiens) [TaxId:9606] [82796] (20 PDB entries)
    Uniprot P00533 702-1018
  8. 1220719Domain d2gs6a_: 2gs6 A: [135578]
    automated match to d1m14a_
    complexed with 112, cl

Details for d2gs6a_

PDB Entry: 2gs6 (more details), 2.6 Å

PDB Description: crystal structure of the active egfr kinase domain in complex with an atp analog-peptide conjugate
PDB Compounds: (A:) Epidermal growth factor receptor

SCOPe Domain Sequences for d2gs6a_:

Sequence, based on SEQRES records: (download)

>d2gs6a_ d.144.1.7 (A:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreats
pkankeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsq
yllnwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhae
ggkvpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekger
lpqppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsp
tdsnfyralmdeedmddvvdadeylip

Sequence, based on observed residues (ATOM records): (download)

>d2gs6a_ d.144.1.7 (A:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikeltspka
nkeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyll
nwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggk
vpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpq
ppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsedmd
dvvdadeylip

SCOPe Domain Coordinates for d2gs6a_:

Click to download the PDB-style file with coordinates for d2gs6a_.
(The format of our PDB-style files is described here.)

Timeline for d2gs6a_: