SCOP 1.75: Domain d1rz8b1: 1rz8 B:1-113

Lineage for d1rz8b1 (1rz8 B:1-113)

Root: SCOP 1.75
Class b: All beta proteins [48724] (174 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (4 families)
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (32 proteins)

Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88544] (36 PDB entries)
Domain d1rz8b1: 1rz8 B:1-113 [98139]
Other proteins in same PDB: d1rz8a1, d1rz8a2, d1rz8b2, d1rz8c1, d1rz8c2, d1rz8d2
part of anti HIV-1 gp120-reactive Fab 17B

Details for d1rz8b1

PDB Entry: 1rz8 (more details), 2.3 Å

PDB Description: crystal structure of human anti-hiv-1 gp120-reactive antibody 17b

PDB Compounds: (B:) Fab 17b heavy chain

SCOP Domain Sequences for d1rz8b1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rz8b1 b.1.1.1 (B:1-113) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 1 [TaxId: 9606]}
evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
gtlvtvss

SCOP Domain Coordinates for d1rz8b1:

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Timeline for d1rz8b1: