Lineage for d1r3ja1 (1r3j A:1-107)

  1. Root: SCOPe 2.04
  2. 1510239Class b: All beta proteins [48724] (176 folds)
  3. 1510240Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1510241Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1510242Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1511401Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1511994Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (213 PDB entries)
    Uniprot P01645 1-106 # 95% sequense identity; KV5L_MOUSE Ig kappa chain V-V region HP 93G7 ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! SQ NA # humanized antibody ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01642 21-115 # ! KV5I_MOUSE Ig kappa chain V-V region L7 precursor
  8. 1512033Domain d1r3ja1: 1r3j A:1-107 [96928]
    Other proteins in same PDB: d1r3ja2, d1r3jb1, d1r3jb2, d1r3jc_
    part of Fab against potassium channel KcsA
    complexed with dga, f09, tl

Details for d1r3ja1

PDB Entry: 1r3j (more details), 1.9 Å

PDB Description: potassium channel kcsa-fab complex in high concentration of tl+
PDB Compounds: (A:) antibody fab fragment light chain

SCOPe Domain Sequences for d1r3ja1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1r3ja1 b.1.1.1 (A:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4 [TaxId: 10090]}
dilltqspailsvspgervsfscrasqsigtdihwyqqrtngsprllikyasesisgips
rfsgsgsgtdftlsinsvesedianyycqqsnrwpftfgsgtkleik

SCOPe Domain Coordinates for d1r3ja1:

Click to download the PDB-style file with coordinates for d1r3ja1.
(The format of our PDB-style files is described here.)

Timeline for d1r3ja1: