Lineage for d1lila1 (1lil A:2-107)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2741614Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2741692Species Human (Homo sapiens), cluster 5 [TaxId:9606] [88540] (8 PDB entries)
    Uniprot Q8N355 20-230 # 94% sequence identity; natural chimera: antibody light chain (Fab HYB3)
  8. 2741700Domain d1lila1: 1lil A:2-107 [20557]
    Other proteins in same PDB: d1lila2, d1lilb2
    part of Bence-Jones protein CLE

Details for d1lila1

PDB Entry: 1lil (more details), 2.65 Å

PDB Description: bence jones protein cle, a lambda iii immunoglobulin light-chain dimer
PDB Compounds: (A:) lambda III bence jones protein cle

SCOPe Domain Sequences for d1lila1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1lila1 b.1.1.1 (A:2-107) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 5 [TaxId: 9606]}
yevtqppslsvspgqtaritcsgeklgdayvcwyqqrpgqspvvviyqdnrrpsgiperf
sgsssgntatltisgtqtldeadyycqvwdsnasvvfgggtkltvlg

SCOPe Domain Coordinates for d1lila1:

Click to download the PDB-style file with coordinates for d1lila1.
(The format of our PDB-style files is described here.)

Timeline for d1lila1:

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Domains from same chain:
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d1lila2