PDB entry 8ics

View 8ics on RCSB PDB site
Description: DNA polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of DNA; soaked in the presence of dctp (1 millimolar) and mncl2 (5 millimolar)
Class: transferase/DNA
Keywords: DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION, DNA REPAIR, NUCLEOTIDYLTRANSFERASE, COMPLEX (NUCLEOTIDYLTRANSFERASE-DNA, TRANSFERASE-DNA complex
Deposited on 1995-12-15, released 1996-11-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.167
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (DNA polymerase beta (e.c.2.7.7.7))
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d8icsa1, d8icsa3, d8icsa4
  • Chain 'P':
    Compound: DNA (5'-d(*tp*cp*tp*ap*ap*tp*g)-3')
  • Chain 'T':
    Compound: DNA (5'-d(*cp*ap*tp*tp*ap*gp*ap*a)-3')
  • Heterogens: MN, NA, DCP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >8icsA (A:)
mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
lgvtgvageplpvdsekdifdyiqwkyrepkdrse

    Sequence, based on observed residues (ATOM records): (download) 
    >8icsA (A:)
etlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtk
iaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrkn
edklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaess
gdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndek
eyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvag
eplpvdsekdifdyiqwkyrepkdrse

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.