PDB entry 7m1y

View 7m1y on RCSB PDB site
Description: The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with ebselen
Class: hydrolase
Keywords: covid-19, coronavirus, SARS, CoV-2, papain-like protease, IDP51000, IDP52003, Center for Structural Genomics of Infectious Diseases, CSGID, HYDROLASE
Deposited on 2021-03-15, released 2021-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-24, with a file datestamp of 2021-03-19.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: papain-like protease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC1 (Start-317)
      • engineered mutation (113)
    Domains in SCOPe 2.08: d7m1ya1, d7m1ya2
  • Chain 'B':
    Compound: papain-like protease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC1
      • engineered mutation (113)
    Domains in SCOPe 2.08: d7m1yb1, d7m1yb2
  • Heterogens: 9JT, ZN, CL, GOL, IOD, FMT, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7m1yA (A:)
snaevrtikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyv
lpnddtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnnsylatal
ltlqqielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhan
ldsckrvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqq
espfvmmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseyk
gpitdvfykensytttik

    Sequence, based on observed residues (ATOM records): (download) 
    >7m1yA (A:)
vrtikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyvlpnd
dtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnnsylatalltlq
qielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhanldsc
krvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqqespf
vmmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseykgpit
dvfykensytttik

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7m1yB (B:)
snaevrtikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyv
lpnddtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnnsylatal
ltlqqielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhan
ldsckrvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqq
espfvmmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseyk
gpitdvfykensytttik

    Sequence, based on observed residues (ATOM records): (download) 
    >7m1yB (B:)
rtikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyvlpndd
tlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnnsylatalltlqq
ielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhanldsck
rvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqqespfv
mmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseykgpitd
vfykensyttti