PDB entry 7lxz

View 7lxz on RCSB PDB site
Description: SARS-CoV-2 S/S2M11/S2L28 Global Refinement
Class: viral protein/immune system
Keywords: Antibody, VIRAL PROTEIN, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2021-03-05, released 2021-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: EM
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (816)
      • engineered mutation (891)
      • engineered mutation (898)
      • engineered mutation (941)
      • engineered mutation (985-986)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (816)
      • engineered mutation (891)
      • engineered mutation (898)
      • engineered mutation (941)
      • engineered mutation (985-986)
  • Chain 'C':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-103)
    Domains in SCOPe 2.08: d7lxzc_
  • Chain 'D':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-103)
    Domains in SCOPe 2.08: d7lxzd_
  • Chain 'E':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-121)
    Domains in SCOPe 2.08: d7lxze_
  • Chain 'F':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-121)
    Domains in SCOPe 2.08: d7lxzf_
  • Chain 'G':
    Compound: S2L28 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-125)
    Domains in SCOPe 2.08: d7lxzg_
  • Chain 'H':
    Compound: S2L28 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-125)
    Domains in SCOPe 2.08: d7lxzh_
  • Chain 'I':
    Compound: S2L28 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-106)
    Domains in SCOPe 2.08: d7lxzi_
  • Chain 'J':
    Compound: S2L28 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-106)
    Domains in SCOPe 2.08: d7lxzj_
  • Chain 'K':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (816)
      • engineered mutation (891)
      • engineered mutation (898)
      • engineered mutation (941)
      • engineered mutation (985-986)
  • Chain 'L':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-103)
    Domains in SCOPe 2.08: d7lxzl_
  • Chain 'M':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-121)
    Domains in SCOPe 2.08: d7lxzm_
  • Chain 'N':
    Compound: S2L28 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-125)
    Domains in SCOPe 2.08: d7lxzn_
  • Chain 'O':
    Compound: S2L28 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LXZ (0-106)
    Domains in SCOPe 2.08: d7lxzo_
  • Heterogens: BMA, FUC, NAG

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzC (C:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzD (D:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzE (E:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzF (F:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzG (G:)
evqlvesggglvnpggslrlscaasgftfsdytihwvrqapgkglewvssissssnyiyy
adsvkgrftisrdnaknslslqmnslraedtavyycardgnaykwllaenvrfdywgqgt
lvtvss

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzH (H:)
evqlvesggglvnpggslrlscaasgftfsdytihwvrqapgkglewvssissssnyiyy
adsvkgrftisrdnaknslslqmnslraedtavyycardgnaykwllaenvrfdywgqgt
lvtvss

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzI (I:)
vtqpasvsgspgqsitisctgtssdvggynyvswyqqhpgkapklmiydvsdrpsgvsnr
fsgsksgntasltisglqaedeadyycssytssstpnwvfgggtklt

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzJ (J:)
vtqpasvsgspgqsitisctgtssdvggynyvswyqqhpgkapklmiydvsdrpsgvsnr
fsgsksgntasltisglqaedeadyycssytssstpnwvfgggtklt

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzL (L:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzM (M:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzN (N:)
evqlvesggglvnpggslrlscaasgftfsdytihwvrqapgkglewvssissssnyiyy
adsvkgrftisrdnaknslslqmnslraedtavyycardgnaykwllaenvrfdywgqgt
lvtvss

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lxzO (O:)
vtqpasvsgspgqsitisctgtssdvggynyvswyqqhpgkapklmiydvsdrpsgvsnr
fsgsksgntasltisglqaedeadyycssytssstpnwvfgggtklt