PDB entry 7k7c

View 7k7c on RCSB PDB site
Description: Crystal structure of diphtheria toxin from crystals obtained at pH 5.5
Class: toxin
Keywords: diptheria toxin, pH dependent conformational changes, toxin
Deposited on 2020-09-22, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-18, with a file datestamp of 2020-11-13.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: diphtheria toxin
    Species: Corynebacterium diphtheriae [TaxId:1717]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5PY51 (Start-535)
      • engineered mutation (51)
      • engineered mutation (148)
      • cloning artifact (536-537)
    Domains in SCOPe 2.08: d7k7ca1, d7k7ca2, d7k7ca3, d7k7ca4
  • Chain 'B':
    Compound: diphtheria toxin
    Species: Corynebacterium diphtheriae [TaxId:1717]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5PY51 (Start-535)
      • engineered mutation (51)
      • engineered mutation (148)
      • cloning artifact (536-537)
    Domains in SCOPe 2.08: d7k7cb1, d7k7cb2, d7k7cb3, d7k7cb4
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k7cA (A:)
mgaddvvdssksfvmenfssyhgtkpgyvdsiqkgiqkpksgtqgnydddwegfystdnk
ydaagysvdnenplsgkaggvvkvtypgltkvlalkvdnaetikkelglslteplmeqvg
teefikrfgdgasrvvlslpfaegsssvkyinnweqakalsveleinfetrgkrgqdamy
eymaqacagnrvrrsvgsslscinldwdvirdktktkieslkehgpiknkmsespnktvs
eekakqyleefhqtalehpelselktvtgtnpvfaganyaawavnvaqvidsetadnlek
ttaalsilpgigsvmgiadgavhhnteeivaqsialsslmvaqaiplvgelvdigfaayn
fvesiinlfqvvhnsynrpayspghktqpflhdgyavswntvedsiirtgfqgesghdik
itaentplpiagvllptipgkldvnkskthisvngrkirmrcraidgdvtfcrpkspvyv
gngvhanlhvafhrsssekihsneissdsigvlgyqktvdhtkvnsklslffeiksma

    Sequence, based on observed residues (ATOM records): (download) 
    >7k7cA (A:)
vvdssksfvmenfssyhgtkpgyvdsiqkgiqkpddwegfystdnkydaagysvdnenpl
sgkaggvvkvtypgltkvlalkvdnaetikkelglslteplmeqvgteefikrfgdgasr
vvlslpfaegsssvkyinnweqakalsveleinfetrgkrgqdamyeymaqacascinld
wdvirdktktkieslkegpikkmsespnktvseekakqyleefhqtalehpelselktvt
gtnpvfaganyaawavnvaqvidsetadnlekttaalsilpgigsvmgiadgavhhntee
ivaqsialsslmvaqaiplvgelgfaaynfvesiinlfqvvhnsynrpayspghktqpfl
hdgyavswntvedsiirtgfqgesghdikitaentplpiagvllptipgkldvnkskthi
svngrkirmrcraidgdvtfcrpkspvyvgngvhanlhvafhrsssekihsneissdsig
vlgyqkkvnsklslffeiksma

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7k7cB (B:)
mgaddvvdssksfvmenfssyhgtkpgyvdsiqkgiqkpksgtqgnydddwegfystdnk
ydaagysvdnenplsgkaggvvkvtypgltkvlalkvdnaetikkelglslteplmeqvg
teefikrfgdgasrvvlslpfaegsssvkyinnweqakalsveleinfetrgkrgqdamy
eymaqacagnrvrrsvgsslscinldwdvirdktktkieslkehgpiknkmsespnktvs
eekakqyleefhqtalehpelselktvtgtnpvfaganyaawavnvaqvidsetadnlek
ttaalsilpgigsvmgiadgavhhnteeivaqsialsslmvaqaiplvgelvdigfaayn
fvesiinlfqvvhnsynrpayspghktqpflhdgyavswntvedsiirtgfqgesghdik
itaentplpiagvllptipgkldvnkskthisvngrkirmrcraidgdvtfcrpkspvyv
gngvhanlhvafhrsssekihsneissdsigvlgyqktvdhtkvnsklslffeiksma

    Sequence, based on observed residues (ATOM records): (download) 
    >7k7cB (B:)
dvvdssksfvmenfssyhgtkpgyvdsiqkgiqkddwegfystdnkydaagysvdnenpl
sgkaggvvkvtypgltkvlalkvdnaetikkelglslteplmeqvgteefikrfgdgasr
vvlslpfaegsssvkyinnweqakalsveleinfetrgkrgqdamyeymaqacascinld
wdvirdktktkieslkepikkmsespnktvseekakqyleefhqtalehpelselktvtg
tnpvfaganyaawavnvaqvidsetadnlekttaalsilpgigsvmgiadgavhhnteei
vaqsialsslmvaqaiplvgegfaaynfvesiinlfqvvhnsynrpayspghktqpflhd
gyavswntvedsiirtgfqgesghdikitaentplpiagvllptipgkldvnkskthisv
ngrkirmrcraidgdvtfcrpkspvyvgngvhanlhvafhrsssekihsneissdsigvl
gyqkkvnsklslffeiksma