PDB entry 7jir
View 7jir on RCSB PDB site
Description: The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder457 inhibitor
Class: HYDROLASE/HYDROLASE inhibitor
Keywords: covid-19, coronavirus, SARS, CoV-2, papain-like protease, IDP51000, Center for Structural Genomics of Infectious Diseases, CSGID, HYDROLASE, HYDROLASE-HYDROLASE inhibitor complex
Deposited on
2020-07-23, released
2020-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2021-03-31, with a file datestamp of
2021-03-26.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: papain-like protease
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Database cross-references and differences (RAF-indexed):
- Uniprot P0DTC1
- engineered mutation (113)
Domains in SCOPe 2.08: d7jira1, d7jira2 - Heterogens: TTT, ZN, CL, MES, ACT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>7jirA (A:)
snaevrtikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyv
lpnddtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnnsylatal
ltlqqielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhan
ldsckrvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqq
espfvmmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseyk
gpitdvfykensytttik
Sequence, based on observed residues (ATOM records): (download)
>7jirA (A:)
vrtikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyvlpnd
dtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnnsylatalltlq
qielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhanldsc
krvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqqespf
vmmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseykgpit
dvfykensyttti