PDB entry 7dvl

View 7dvl on RCSB PDB site
Description: Crystal Structure of the Catalytic Domain of Botulinum Neurotoxin Subtype A3
Class: toxin
Keywords: Botulinum Neurotoxin, Catalytic Domain, activity, stability, TOXIN
Deposited on 2021-01-13, released 2021-04-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bont/A3
    Species: Clostridium botulinum [TaxId:1491]
    Gene: bont, FDC09_07905
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3IV24 (2-418)
      • expression tag (0-1)
      • engineered mutation (225)
      • engineered mutation (367)
    Domains in SCOPe 2.08: d7dvla1, d7dvla2
  • Chain 'B':
    Compound: Bont/A3
    Species: Clostridium botulinum [TaxId:1491]
    Gene: bont, FDC09_07905
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3IV24 (2-418)
      • expression tag (0-1)
      • engineered mutation (225)
      • engineered mutation (367)
    Domains in SCOPe 2.08: d7dvlb1, d7dvlb2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7dvlA (A:)
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lnpppeakqvpvsyydstylstdnekdnylkgviklfdriystglgrmllsfivkgipfw
ggstidtelkvidtncinviepggsyrseelnlvitgpsadiiqfecksfghdvfnltrn
gygstqyirfspdftfgfeeslevdtnpllgagtfatdpavtlahqlihaahrlygiain
pnrvlkvktnayyemsglevsfeelrtfggndtnfidslwqkkfsrdaydnlqniariln
eaktivgtttplqymknifirkyflsedasgkisvnkaafkefyrvltrgftelefvnpf
kvinrktflnfdkavfrinivpdenytinegfnlegansngqnteinsrnftrlknftg

    Sequence, based on observed residues (ATOM records): (download) 
    >7dvlA (A:)
smpfvnkqfnyrdpvngvdiayikipnagqmqpvkafkihegvwviperdtftnpeegdl
npppeakqvpvsyydstylstdnekdnylkgviklfdriystglgrmllsfivkgipfwg
gstidtelkvidtncinviepggsyrseelnlvitgpsadiiqfecksfghdvfnltrng
ygstqyirfspdftfgfeegtfatdpavtlahqlihaahrlygiainpnrvlkvktnayy
emsglevsfeelrtfggndtnfidslwqkkfsrdaydnlqniarilneaktivgtttplq
ymknifirkyflsedasgkisvnkaafkefyrvltrgftelefvnpfkvinrktflnfdk
avfrinivpdenytinegfnlegansngqnteinsrnftrlknft

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7dvlB (B:)
gsmpfvnkqfnyrdpvngvdiayikipnagqmqpvkafkihegvwviperdtftnpeegd
lnpppeakqvpvsyydstylstdnekdnylkgviklfdriystglgrmllsfivkgipfw
ggstidtelkvidtncinviepggsyrseelnlvitgpsadiiqfecksfghdvfnltrn
gygstqyirfspdftfgfeeslevdtnpllgagtfatdpavtlahqlihaahrlygiain
pnrvlkvktnayyemsglevsfeelrtfggndtnfidslwqkkfsrdaydnlqniariln
eaktivgtttplqymknifirkyflsedasgkisvnkaafkefyrvltrgftelefvnpf
kvinrktflnfdkavfrinivpdenytinegfnlegansngqnteinsrnftrlknftg

    Sequence, based on observed residues (ATOM records): (download) 
    >7dvlB (B:)
smpfvnkqfnyrdpvngvdiayikipnagqmqpvkafkihegvwviperdtftnpeegdl
npppeakqvpvsyydstylstdnekdnylkgviklfdriystglgrmllsfivkgipfwg
gstidtelkvidtncinviepggsyrseelnlvitgpsadiiqfecksfghdvfnltrng
ygstqyirfspdftfgfeeslgtfatdpavtlahqlihaahrlygiainpnrvlkvktna
yyemsglevsfeelrtfggndtnfidslwqkkfsrdaydnlqniarilneaktivgtttp
lqymknifirkyflsedasgkisvnkaafkefyrvltrgftelefvnpfkvinrktflnf
dkavfrinivpdenytinegfnlegansngqnteinsrnftrlknft