PDB entry 7c8d

View 7c8d on RCSB PDB site
Description: Cryo-EM structure of cat ACE2 and SARS-CoV-2 RBD
Class: hydrolase/viral protein
Keywords: ACE2, SARS-CoV-2, Cryo-EM, complex, PROTEIN BINDING, HYDROLASE-VIRAL PROTEIN complex
Deposited on 2020-05-29, released 2020-09-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: EM
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Angiotensin-converting enzyme 2
    Species: Felis catus [TaxId:9685]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7c8da_
  • Chain 'B':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7c8db_
  • Heterogens: ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >7c8dA (A:)
    mqstteelaktflekfnheaeelsyqsslaswnyntnitdenvqkmneagakwsafyeeq
    sklaktyplaeihnttvkrqlqalqqsgssvlsadksqrlntilnamstiystgkacnpn
    npqeclllepglddimenskdynerlwawegwraevgkqlrplyeeyvalknemaranny
    edygdywrgdyeeewtdgynysrsqlikdvehtftqikplyqhlhayvraklmdtypsri
    sptgclpahllgdmwgrfwtnlypltvpfgqkpnidvtdamvnqswdarrifkeaekffv
    svglpnmtqgfwensmltepgdsrkvvchptawdlgkgdfrikmctkvtmddfltahhem
    ghiqydmayavqpfllrnganegfheavgeimslsaatpnhlktigllspgfsedsetei
    nfllkqaltivgtlpftymlekwrwmvfkgeipkeqwmqkwwemkreivgvvepvphdet
    ycdpaslfhvandysfiryytrtiyqfqfqealcriakhegplhkcdisnsseagkkllq
    mltlgkskpwtlalehvvgekkmnvtpllkyfeplftwlkeqnrnsfvgwntdwrpyadq
    sikvrislksalgdeayewndnemylfrssvayamreyfskvknqtipfvednvwvsnlk
    prisfnffvtasknvsdviprseveeairmsrsrindafrlddnsleflgiqptlsppyq
    ppvthhhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >7c8dA (A:)
    qstteelaktflekfnheaeelsyqsslaswnyntnitdenvqkmneagakwsafyeeqs
    klaktyplaeihnttvkrqlqalqqsgssvlsadksqrlntilnamstiystgkacnpnn
    pqeclllepglddimenskdynerlwawegwraevgkqlrplyeeyvalknemarannye
    dygdywrgdyeeewtdgynysrsqlikdvehtftqikplyqhlhayvraklmdtypsris
    ptgclpahllgdmwgrfwtnlypltvpfgqkpnidvtdamvnqswdarrifkeaekffvs
    vglpnmtqgfwensmltepgdsrkvvchptawdlgkgdfrikmctkvtmddfltahhemg
    hiqydmayavqpfllrnganegfheavgeimslsaatpnhlktigllspgfsedsetein
    fllkqaltivgtlpftymlekwrwmvfkgeipkeqwmqkwwemkreivgvvepvphdety
    cdpaslfhvandysfiryytrtiyqfqfqealcriakhegplhkcdisnsseagkkllqm
    ltlgkskpwtlalehvvgekkmnvtpllkyfeplftwlkeqnrnsfvgwntdwrpya
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >7c8dB (B:)
    tnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcf
    tnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyl
    yrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvv
    lsfellhapatvcgp