PDB entry 7c7i

View 7c7i on RCSB PDB site
Description: Crystal structure of SHANK3 SPN domain in complex with GTP-bound Rap1b(E30D,K31E)
Class: protein binding
Keywords: SHANK3, Rap1b, SPN, Ras, PROTEIN BINDING
Deposited on 2020-05-25, released 2021-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras-related protein Rap-1b
    Species: Homo sapiens [TaxId:9606]
    Gene: RAP1B, OK/SW-cl.11
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61224 (0-166)
      • engineered mutation (29-30)
    Domains in SCOPe 2.08: d7c7ia_
  • Chain 'B':
    Compound: Ras-related protein Rap-1b
    Species: Homo sapiens [TaxId:9606]
    Gene: RAP1B, OK/SW-cl.11
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61224 (0-166)
      • engineered mutation (29-30)
    Domains in SCOPe 2.08: d7c7ib_
  • Chain 'C':
    Compound: SH3 and multiple ankyrin repeat domains protein 3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: SH3 and multiple ankyrin repeat domains protein 3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GTP, MG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7c7iA (A:)
mreyklvvlgsggvgksaltvqfvqgifvdeydptiedsyrkqvevdaqqcmleildtag
teqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkcdl
edervvgkeqgqnlarqwnncaflessakskinvneifydlvrqinr

    Sequence, based on observed residues (ATOM records): (download) 
    >7c7iA (A:)
mreyklvvlgsggvgksaltvqfvqgifvdeydptiedsyrkqvevdaqqcmleildtag
tqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkcdle
dervvgkeqgqnlarqwnncaflessakskinvneifydlvrqinr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7c7iB (B:)
mreyklvvlgsggvgksaltvqfvqgifvdeydptiedsyrkqvevdaqqcmleildtag
teqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkcdl
edervvgkeqgqnlarqwnncaflessakskinvneifydlvrqinr

    Sequence, based on observed residues (ATOM records): (download) 
    >7c7iB (B:)
mreyklvvlgsggvgksaltvqfvqgifvdeydptiedsyrkqvevdaqqcmleildtag
tqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkcdle
dervvgkeqgqnlarqwnncaflessakskinvneifydlvrqinr

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.